DE-8

DE-8.2

Submodule 24 genes

Vesicular trafficking and intracellular transport

This 24-gene module includes ANKRD26, TSGA10, STX8, HHAT, and FGGY, with enrichment in vesicular transport, intracellular trafficking, and membrane organization. Knockdown of SOX17, EOMES, and GATA4 activates this module. Knockdown of FOXA2, GATA6, and CDX2 represses this module.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (23)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z