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DE-5.11

Submodule 17 genes

Ciliary structure and metabolic function

This module contains 17 genes including HLA-E, HADHB, MAP9, TCTN1, and ALDH6A1, with enrichment for cilium components. No transcription factor knockdown data are available for this module.

Key terms: positive regulation of antibody-dependent cellular cytotoxicity natural killer cell cytokine production regulation of natural killer cell cytokine production positive regulation of natural killer cell cytokine production Notable genes: HLA-E HADHB MAP9 ALDH6A1 TCTN1 DLGAP1-AS1 TSPYL1 CRIPT

TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding ↑ ↓
Perturbation only ↑ ↓
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).

Module Genes (17)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z
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