This module contains 48 genes including IGF1R, APC, TCF7L2, CDH2, and MYH9, with enrichment in Wnt signaling, cell adhesion, and cytoskeletal organization. Knockdown of SMARCC1 and CNBP activates this module. No repressing transcription factors were identified.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.