This 11-gene module includes SATB1, KDM6B, BTG2, TERF2IP, and TP53INP1, with top enriched terms related to chromatin remodeling, histone modification, and cellular stress responses. Knockdown of SOX17 activates this module, while knockdown of EOMESODERMIN represses it. No additional TF perturbation data are available for this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.