This module contains 12 genes including CLIC4, KPNA1, ZMYND11, TRIM71, and SCAF4, enriched for nucleocytoplasmic transport and chromatin remodeling functions. Knockdown of MIXL1, SMAD3, ARID1A, and SMARCC1 activates this module. Knockdown of DR1, SMAD5, SOX4, and SOX11 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.