Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for UBTD2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = UBTD2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of UBTD2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:172,005,757–172,007,902 | 276.9 kb | Distal (>10kb) Multiome | 919 | |
| chr5:172,008,642–172,009,211 | 274.8 kb | Distal (>10kb) Multiome | 162 | |
| chr5:172,187,117–172,188,967 | 95.3 kb | Distal (>10kb) Multiome | 988 | |
| chr5:172,282,945–172,284,922 | 244 bp | At TSS Multiome | 857 | |
| chr5:172,293,389–172,293,747 | 9.6 kb | Proximal (<10kb) | 322 | |
| chr5:172,453,197–172,453,607 | 169.4 kb | Distal (>10kb) Multiome | 249 | |
| chr5:172,453,730–172,456,312 | 170.8 kb | Distal (>10kb) Multiome | 677 | |
| chr5:172,478,999–172,479,594 | 195.4 kb | Distal (>10kb) Multiome | 365 |
Genomic view of the UBTD2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.