This 15-gene module includes LYN, SATB2, PAWR, TOX3, and LAMC1, with enrichment in lymphoid differentiation, cell adhesion, and extracellular matrix organization. Knockdown of SOX17 activates this module, while knockdown of FOXA2 and GSC repress it.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.