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DE-1.57

Submodule 10 genes

RNA processing and protein phosphatase activity

This module contains 10 genes including HNRNPA1, HNRNPC, ABCE1, PPP1CC, and PPID, with top enriched terms related to RNA processing, mRNA splicing, and protein phosphatase activity. No transcription factor knockdown data are available for this module. No binding transcription factor data are provided.

Key terms: negative regulation of telomere maintenance via telomere lengthening negative regulation of DNA biosynthetic process negative regulation of telomere maintenance via telomerase chromosome organization Notable genes: HNRNPA1 HNRNPC ABCE1 PPP1CC PPID DAZAP1 BOD1 RSL1D1

TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding ↑ ↓
Perturbation only ↑ ↓
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).

Module Genes (10)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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High z
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