DE-1

DE-1.28

Submodule 17 genes

Ribosome biogenesis and ribonucleoprotein assembly

This 17-gene module includes YY1, PPP2CA, HSPA9, DDX21, and DHX36, with enrichment for ribosome biogenesis and ribonucleoprotein complex biogenesis. No TF knockdown data are available for this module, so we cannot determine which transcription factors activate or repress its expression during ESC-to-DE differentiation.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (17)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z