chr10:80,076,334–80,077,082

chr10 : 80,076,334 – 80,077,082

748 bp 10 TFs 5 linked genes

This 748 bp open chromatin element is linked to 5 target genes and is bound by 10 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TMEM254		1.6 kb	Proximal	Proximity
TMEM254-AS1		1.8 kb	Proximal	Proximity
ANXA11		129.0 kb	Distal	Multiome
ENSG00000283913		171.7 kb	Distal	Multiome
NUTM2B-AS1		250.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

10 transcription factors

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 405 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 226 bp overlap

ChIP DE DE-FOXA2-1 688 bp overlap

ChIP DE DE-FOXA2-2 714 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 688 bp overlap

ChIP DE DE-GATA4-2 748 bp overlap

ChIP foregut GSE117136.GATA4.foregut 260 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 631 bp overlap

ChIP DE DE-GATA6-2 748 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 634 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 471 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 53 bp overlap

SMAD2-3 2 datasets

ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 152 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 677 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 368 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 307 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 412 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 561 bp overlap

ZNF664 1 dataset

ChIP HEK293 ENCFF343XSW 79 bp overlap