DE-8

DE-8.1

Submodule 41 genes

Macroautophagy and protein modification pathways

This 41-gene module includes HTT, OGT, RNF213, PFKFB3, and CDKL5, and is enriched for macroautophagy. No transcription factor knockdown data are available for this module, limiting inference of its regulatory control during ESC-to-DE differentiation.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (41)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z