This module contains 20 genes including MBD4, MAZ, TXNDC5, ING2, and PLEKHO1, with enrichment in DNA methylation and chromatin remodeling processes. Knockdown of SMAD5 and SOX17 activates this module. Knockdown of ARID1A and MIXL1 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.