This module contains 28 genes including MSH3, MTAP, AHI1, FANCL, and NSD3, enriched for DNA repair and mismatch recognition functions. Knockdown of SOX17 and ZC3H3 activates this module. Knockdown of SOX11, ZNF532, and SOX4 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.