DE-2

DE-2.46

Submodule 10 genes

Extracellular matrix and lipid transport factors

This module contains 10 genes including THBS4, ATP8B1, and CLYBL, with top enriched terms related to extracellular matrix organization and lipid transport. Knockdown of SOX17, EOMESODERMIN, and GATA4 activates this module. Knockdown of NANOG represses this module.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (10)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

| |
Low
High z