DE-2

DE-2.10

Submodule 19 genes

Zinc finger and membrane protein regulation

This 19-gene module includes TMEM67, PRDM10, IQCK, ZNF655, and ZNF251, with limited enriched biological terms available. No transcription factor knockdown data are provided for this module, preventing identification of upstream regulators during ESC-to-DE differentiation.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (17)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z