DE-1

DE-1.48

Submodule 11 genes

Nucleotide metabolism and oxidative stress response

This module comprises 11 genes including NME1, PABPN1, PRDX4, MTCH2, and SMS, enriched for nucleotide metabolism, oxidative stress response, and apoptosis regulation. No transcription factor knockdown data are available for this module, preventing identification of upstream regulators.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (11)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z