This module contains 13 genes including BSG, KRT10, CALM3, EI24, and DAD1, with top enriched terms related to protein processing, endoplasmic reticulum organization, and protein folding. Knockdown of FOXA2 activates this module, while knockdown of SOX17 and GATA4 repress it. This pattern suggests the module is suppressed by endoderm-specifying transcription factors during normal DE differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.