MEX3A

mex-3 RNA binding family member A | RNF162, RKHD4

Enables RNA binding activity. Located in P-body and cytosol. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-10 DE-10.6 Developmental clusters: GC6

Biological processes 9 terms

P-body (GO:0000932)P-body (GO:0000932)RNA binding (GO:0003723)RNA binding (GO:0003723)RNA binding (GO:0003723)cytoplasm (GO:0005737)cytosol (GO:0005829)nucleic acid binding (GO:0003676)nucleus (GO:0005634)

Expression (TPM)

TFs regulating MEX3A 0 TFs

Transcription factors with Perturb-seq knockdown data for MEX3A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MEX3A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to MEX3A

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MEX3A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr1:155,806,537–155,807,073	275.7 kb	Distal (>10kb) Multiome	15
chr1:155,856,932–155,857,529	225.2 kb	Distal (>10kb) Multiome	639
chr1:155,859,095–155,860,745	223.0 kb	Distal (>10kb) Multiome	632
chr1:155,910,686–155,911,579	171.1 kb	Distal (>10kb) Multiome	691
chr1:155,934,107–155,934,787	148.0 kb	Distal (>10kb) Multiome	872
chr1:155,976,727–155,977,187	105.6 kb	Distal (>10kb) Multiome	316
chr1:155,977,296–155,979,264	103.7 kb	Distal (>10kb) Multiome	698
chr1:156,020,469–156,021,128	61.5 kb	Distal (>10kb) Multiome	558
chr1:156,052,923–156,055,358	27.6 kb	Distal (>10kb) Multiome	1053
chr1:156,060,806–156,061,738	21.3 kb	Distal (>10kb) Multiome	318
chr1:156,063,507–156,064,184	18.6 kb	Distal (>10kb) Multiome	199
chr1:156,073,800–156,074,094	7.6 kb	Proximal (<10kb)	76
chr1:156,076,488–156,077,355	5.5 kb	Proximal (<10kb) Multiome	246
chr1:156,081,942–156,083,586	133 bp	At TSS Multiome	670
chr1:156,090,597–156,091,028	8.9 kb	Proximal (<10kb)	334
chr1:156,105,879–156,107,316	24.1 kb	Distal (>10kb) Multiome	663
chr1:156,114,184–156,115,669	32.2 kb	Distal (>10kb) Multiome	824
chr1:156,123,520–156,124,091	41.3 kb	Distal (>10kb) Multiome	679
chr1:156,129,945–156,130,610	47.9 kb	Distal (>10kb) Multiome	733
chr1:156,146,058–156,146,760	63.9 kb	Distal (>10kb) Multiome	429
chr1:156,149,593–156,150,242	67.5 kb	Distal (>10kb) Multiome	194
chr1:156,160,602–156,161,218	78.6 kb	Distal (>10kb) Multiome	218
chr1:156,181,487–156,182,119	99.3 kb	Distal (>10kb) Multiome	145
chr1:156,184,002–156,185,155	101.9 kb	Distal (>10kb) Multiome	216
chr1:156,193,531–156,194,375	111.5 kb	Distal (>10kb) Multiome	751
chr1:156,212,611–156,213,686	130.7 kb	Distal (>10kb) Multiome	893
chr1:156,245,413–156,246,269	163.3 kb	Distal (>10kb) Multiome	380
chr1:156,282,165–156,283,323	200.4 kb	Distal (>10kb) Multiome	973
chr1:156,291,233–156,291,857	209.1 kb	Distal (>10kb) Multiome	518
chr1:156,337,825–156,339,056	256.0 kb	Distal (>10kb) Multiome	836
chr1:156,356,873–156,357,393	274.6 kb	Distal (>10kb) Multiome	506
chr1:156,368,893–156,369,552	286.8 kb	Distal (>10kb) Multiome	529

Genome Browser

Genomic view of the MEX3A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.