This 52-gene module includes NRG1, VIM, BMP4, NRP1, and FSHR, with enrichment for positive regulation of cell differentiation and developmental growth, as well as receptor complex and signaling receptor activity. Knockdown of SOX11 activates this module. Knockdown of ARID1A represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.