This module contains 10 genes including STX17, TRDMT1, KCTD20, TUBD1, and PTGR3, with enrichment in vesicle-mediated transport and protein modification pathways. Knockdown of SOX17 activates this module, while knockdown of EOMESODERMIN represses it. These results suggest coordinated regulation of cellular transport machinery during endoderm differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.