Module DE-4.15 contains 17 genes including TJP1, ATP2A2, and MERTK, with enrichment in tight junction organization, cell adhesion, and calcium signaling. Knockdown of ZNF628, CTBP1, DNMT1, ZIC3, and SOX11 activates this module. Knockdown of DNAJC19 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.