This module contains 21 genes, including RIGI, RARB, PLCE1, PRKCQ, and S1PR3, enriched for molecular transducer activity and signaling receptor activity. Knockdown of SOX17, EOMESODERMIN, and GATA4 activates this module. Knockdown of NANOG, OCT4, and SOX2 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.