This 26-gene module includes TNC, GPC3, ADGRL3, PRDM5, and ARHGAP26, with enrichment in extracellular matrix organization, cell adhesion, and developmental processes. Knockdown of ARID1A, MIXL1, SMARCC1, SMAD3, and SNAI1 activates this module. Knockdown of SMAD5, HES1, MARS, DR1, and HNF1B represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.