This module contains 27 genes including SNCA, NTF3, GRK5, GRHL2, and TRPM6, with enrichment in neuronal development, epithelial differentiation, and ion channel regulation. Knockdown of SOX17 activates this module, while knockdown of EOMESODERMIN, FOXA2, and GSC represses it.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.