This 10-gene module includes PBRM1, FAT1, ARSB, SP4, and PAXIP1, with enrichment in chromatin remodeling, cell adhesion, and extracellular matrix organization. Knockdown of SOX17 and FOXA2 activates this module. Knockdown of EOMESODERMIN represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.