This module contains 28 genes including PRKN, ALCAM, FUT8, ACYP2, and ZBTB20, with enrichment in protein modification and cell adhesion pathways. Knockdown of ARID1A, SMAD4, and FOXH1 activates this module. Knockdown of SMAD5, SOX11, PRDM5, SOX4, and HNF1B represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.