This 19-gene module includes FHIT, TIAM1, SMYD3, SOX5, and RAD51B, with enrichment in DNA repair and chromatin remodeling processes. Knockdown of CNBP and ARID1A activates this module. Knockdown of ZNF532 and SOX11 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.