This module contains 11 genes including CETN2, FRG1, TMCO1, NDUFA1, and SELENOK, with enrichment in mitochondrial oxidative phosphorylation, mitochondrial function, and protein synthesis pathways. Knockdown of KLF6 and SOX17 activates this module. Knockdown of KLF8 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.