This 12-gene module includes NAA10, SDHC, CLPP, EIF4E2, and TRAPPC4, with enrichment in mitochondrial oxidative phosphorylation, protein synthesis, and mitochondrial organization. Knockdown of SOX17 and FOXH1 activates this module. No repressing TFs were identified for this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.