DE-1

DE-1.37

Submodule 13 genes

Mitochondrial function and metabolic homeostasis

This module contains 13 genes including ACP1, MIEN1, MPST, JTB, and DNAJC19, with top enriched terms related to mitochondrial organization, metabolic processes, and cellular homeostasis. No transcription factor knockdown data are available for this module. The functional role of these genes in endoderm differentiation remains to be characterized through additional experimental validation.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (13)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z