This 20-gene module includes GNAS, PGK1, SSBP1, UBE2L3, and PUF60, and is significantly enriched for respiratory chain complex components, aerobic respiration, oxidative phosphorylation, and cellular respiration, along with transmembrane transporter complexes involved in proton and cation transport. No transcription factor knockdown data are available for this module, preventing identification of upstream regulators.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.