Located in centriolar satellite. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TEX9. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TEX9 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TEX9, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:55,992,927–55,994,423 | 250.4 kb | Distal (>10kb) Multiome | 728 | |
| chr15:56,242,930–56,244,999 | 126 bp | At TSS Multiome | 643 | |
| chr15:56,245,857–56,246,386 | 2.2 kb | Proximal (<10kb) Multiome | 738 | |
| chr15:56,248,336–56,248,566 | 4.4 kb | Proximal (<10kb) | 24 | |
| chr15:56,249,186–56,249,369 | 5.2 kb | Proximal (<10kb) | 51 | |
| chr15:56,251,292–56,252,202 | 7.3 kb | Proximal (<10kb) | 187 | |
| chr15:56,364,869–56,365,893 | 121.4 kb | Distal (>10kb) Multiome | 591 | |
| chr15:56,464,770–56,465,573 | 221.2 kb | Distal (>10kb) Multiome | 565 | |
| chr15:56,537,662–56,538,339 | 294.1 kb | Distal (>10kb) Multiome | 170 |
Genomic view of the TEX9 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.