GPATCH4

G-patch domain containing 4 (gene/pseudogene) | DKFZP434F1735, FLJ20249, GPATC4

Enables RNA binding activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-1 Developmental clusters: GC4

Biological processes 4 terms

RNA binding (GO:0003723)nucleic acid binding (GO:0003676)nucleolus (GO:0005730)protein binding (GO:0005515)

Expression (TPM)

TFs regulating GPATCH4 0 TFs

Transcription factors with Perturb-seq knockdown data for GPATCH4. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GPATCH4 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to GPATCH4

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GPATCH4, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr1:156,337,825–156,339,056	263.0 kb	Distal (>10kb) Multiome	836
chr1:156,356,873–156,357,393	244.4 kb	Distal (>10kb) Multiome	506
chr1:156,368,893–156,369,552	232.2 kb	Distal (>10kb) Multiome	529
chr1:156,420,712–156,422,291	179.7 kb	Distal (>10kb) Multiome	569
chr1:156,429,277–156,430,847	171.6 kb	Distal (>10kb) Multiome	231
chr1:156,432,112–156,432,986	168.8 kb	Distal (>10kb) Multiome	50
chr1:156,439,076–156,440,265	161.5 kb	Distal (>10kb) Multiome	264
chr1:156,456,348–156,457,982	144.7 kb	Distal (>10kb) Multiome	1033
chr1:156,499,927–156,501,599	100.5 kb	Distal (>10kb) Multiome	950
chr1:156,504,626–156,505,685	96.1 kb	Distal (>10kb) Multiome	911
chr1:156,572,298–156,572,749	28.9 kb	Distal (>10kb) Multiome	580
chr1:156,583,883–156,584,356	17.4 kb	Distal (>10kb) Multiome	183
chr1:156,591,252–156,592,285	9.7 kb	Proximal (<10kb) Multiome	706
chr1:156,601,188–156,601,796	37 bp	At TSS Multiome	759
chr1:156,608,164–156,608,359	6.7 kb	Proximal (<10kb)	254
chr1:156,624,123–156,624,848	23.1 kb	Distal (>10kb) Multiome	472
chr1:156,641,772–156,642,623	40.6 kb	Distal (>10kb) Multiome	211
chr1:156,657,279–156,657,727	56.1 kb	Distal (>10kb) Multiome	357
chr1:156,659,788–156,660,816	58.7 kb	Distal (>10kb) Multiome	901
chr1:156,673,575–156,674,145	72.4 kb	Distal (>10kb) Multiome	269
chr1:156,676,488–156,677,779	75.9 kb	Distal (>10kb) Multiome	449
chr1:156,689,084–156,690,144	88.1 kb	Distal (>10kb) Multiome	508
chr1:156,692,653–156,693,825	91.7 kb	Distal (>10kb) Multiome	493
chr1:156,703,427–156,704,626	102.4 kb	Distal (>10kb) Multiome	182
chr1:156,704,839–156,707,238	104.7 kb	Distal (>10kb) Multiome	728
chr1:156,708,331–156,708,813	107.0 kb	Distal (>10kb) Multiome	108
chr1:156,728,152–156,729,282	127.2 kb	Distal (>10kb) Multiome	815
chr1:156,740,482–156,741,987	139.8 kb	Distal (>10kb) Multiome	1012
chr1:156,746,390–156,748,386	145.8 kb	Distal (>10kb) Multiome	750
chr1:156,751,012–156,752,594	150.4 kb	Distal (>10kb) Multiome	869
chr1:156,766,695–156,768,280	165.9 kb	Distal (>10kb) Multiome	967
chr1:156,813,606–156,814,470	212.6 kb	Distal (>10kb) Multiome	756
chr1:156,845,268–156,845,794	244.1 kb	Distal (>10kb) Multiome	73
chr1:156,848,614–156,849,138	247.5 kb	Distal (>10kb) Multiome	129
chr1:156,860,147–156,861,294	259.1 kb	Distal (>10kb) Multiome	484
chr1:156,862,753–156,863,585	261.8 kb	Distal (>10kb) Multiome	268
chr1:156,892,162–156,892,597	291.0 kb	Distal (>10kb) Multiome	439
chr1:156,893,409–156,893,975	292.3 kb	Distal (>10kb) Multiome	143

Genome Browser

Genomic view of the GPATCH4 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.