This module contains 10 genes including KCNQ1OT1, NUMB, CTNNA3, BTBD9, and FBXL17, with enrichment in cell junction organization and membrane-associated processes. Knockdown of HNF1B represses this module, suggesting HNF1B supports its expression during endoderm differentiation. No TFs whose knockdown activates this module were identified in the data.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.