DE-3

DE-3.14

Submodule 21 genes

Ubiquitin ligase and coactivator signaling pathway

This module contains 21 genes including NCOA1, CBLB, WWP1, and NEO1, with top enriched terms related to ubiquitin ligase activity, protein modification, and coactivator function. No transcription factor knockdown data are available for this module. No additional regulatory information is provided.

Notable genes: NCOA1 CBLB WWP1 NEO1 MEIS2 HCN1 BMP5 SSBP2

TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (21)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z