This module contains 22 genes including NCOA2, PBX1, MSI2, KMT2C, and CLASP1, with enriched terms related to chromatin remodeling, histone modification, and stem cell maintenance. Knockdown of SOX2, OCT4, and NANOG activates this module. Knockdown of FOXA2, GATA4, and GATA6 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.