DE-3

DE-3.12

Submodule 24 genes

GTPase regulation and nucleotide signaling

This module contains 24 genes including HDAC8, ST6GAL1, CASK, ASAP1, and KALRN, enriched for GTPase regulator activity and nucleoside-triphosphatase regulator activity. No transcription factor knockdown data are available for this module, limiting inference of regulatory control during ESC-to-DE differentiation.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (24)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z