DE-12

DE-12.2

Submodule 33 genes

Metabolic and transport gene expression

This module comprises 33 genes including CHRM3, STS, PDK1, SLCO1A2, and TNNT1, with enrichment in metabolic processes and solute carrier activity. Knockdown of SETDB1, DNMT1, and ZNF850 represses this module, suggesting these factors support its expression.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (30)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z