This module contains 43 genes including SDHD, AIMP1, C1GALT1C1, WDR77, and MCFD2, with enrichment for mitochondrial membrane components, particularly the mitochondrial inner membrane and organelle inner membrane structures. Knockdown of SOX17, NANOG, and OCT4 activates this module. Knockdown of FOXA2, GATA4, and GATA6 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.