ZNF808

zinc finger protein 808

Enables transcription cis-regulatory region binding activity. Involved in cell differentiation; negative regulation of gene expression; and pancreas development. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-5

Biological processes 11 terms

cell differentiation (GO:0030154)negative regulation of gene expression (GO:0010629)negative regulation of transcription by RNA polymerase II (GO:0000122)nucleus (GO:0005634)nucleus (GO:0005634)pancreas development (GO:0031016)regulation of DNA-templated transcription (GO:0006355)regulation of gene expression (GO:0010468)sequence-specific double-stranded DNA binding (GO:1990837)transcription cis-regulatory region binding (GO:0000976)transcription cis-regulatory region binding (GO:0000976)

Expression (TPM)

TFs regulating ZNF808 0 TFs

Transcription factors with Perturb-seq knockdown data for ZNF808. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF808 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to ZNF808

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF808, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr19:52,269,012–52,270,193	266.4 kb	Distal (>10kb) Multiome	782
chr19:52,296,552–52,297,775	238.8 kb	Distal (>10kb) Multiome	561
chr19:52,335,886–52,336,825	199.8 kb	Distal (>10kb) Multiome	373
chr19:52,338,866–52,339,647	196.7 kb	Distal (>10kb) Multiome	56
chr19:52,492,205–52,493,529	43.1 kb	Distal (>10kb) Multiome	178
chr19:52,526,868–52,528,322	8.5 kb	Proximal (<10kb) Multiome	602
chr19:52,535,433–52,536,654	13 bp	At TSS Multiome	273
chr19:52,558,780–52,559,576	23.2 kb	Distal (>10kb) Multiome	17
chr19:52,569,672–52,570,898	34.2 kb	Distal (>10kb) Multiome	555
chr19:52,600,732–52,601,970	65.2 kb	Distal (>10kb) Multiome	412
chr19:52,637,710–52,638,958	102.4 kb	Distal (>10kb) Multiome	473
chr19:52,690,252–52,691,142	154.6 kb	Distal (>10kb) Multiome	540
chr19:52,734,568–52,736,125	200.1 kb	Distal (>10kb) Multiome	473
chr19:52,741,322–52,742,486	206.2 kb	Distal (>10kb) Multiome	114
chr19:52,786,717–52,787,643	250.9 kb	Distal (>10kb) Multiome	439

Genome Browser

Genomic view of the ZNF808 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.