This gene encodes a member of the zinc-finger protein family. The encoded protein contains seven C2H2-type zinc fingers and a KRAB domain, but its function has yet to be determined. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2014]
Transcription factors with Perturb-seq knockdown data for ZNF302. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF302 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF302, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:34,404,022–34,405,020 | 273.3 kb | Distal (>10kb) Multiome | 883 | |
| chr19:34,428,165–34,428,863 | 249.3 kb | Distal (>10kb) Multiome | 809 | |
| chr19:34,480,917–34,482,711 | 196.1 kb | Distal (>10kb) Multiome | 520 | |
| chr19:34,501,375–34,501,856 | 176.0 kb | Distal (>10kb) Multiome | 590 | |
| chr19:34,668,047–34,668,472 | 9.2 kb | Proximal (<10kb) Multiome | 24 | |
| chr19:34,676,923–34,678,053 | 51 bp | At TSS Multiome | 728 | |
| chr19:34,733,416–34,734,655 | 56.5 kb | Distal (>10kb) Multiome | 1008 | |
| chr19:34,772,709–34,773,413 | 95.5 kb | Distal (>10kb) Multiome | 680 | |
| chr19:34,920,040–34,921,057 | 242.8 kb | Distal (>10kb) Multiome | 309 | |
| chr19:34,926,731–34,927,343 | 249.3 kb | Distal (>10kb) Multiome | 741 | |
| chr19:34,963,909–34,964,414 | 286.5 kb | Distal (>10kb) Multiome | 645 |
Genomic view of the ZNF302 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.