Predicted to enable phosphatidylinositol binding activity. Involved in positive regulation of autophagosome assembly and protein transport. Is active in early endosome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNX30. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNX30 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNX30, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:112,486,079–112,487,780 | 264.0 kb | Distal (>10kb) Multiome | 1004 | |
| chr9:112,717,577–112,718,753 | 32.6 kb | Distal (>10kb) Multiome | 751 | |
| chr9:112,750,159–112,751,980 | 80 bp | At TSS Multiome | 907 | |
| chr9:112,754,657–112,754,978 | 3.9 kb | Proximal (<10kb) | 132 | |
| chr9:112,771,981–112,772,634 | 21.5 kb | Distal (>10kb) Multiome | 89 | |
| chr9:113,011,893–113,012,348 | 261.4 kb | Distal (>10kb) Multiome | 444 |
Genomic view of the SNX30 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.