Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be involved in protein transport. Predicted to be located in cytoplasmic vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNX24. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNX24 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNX24, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:122,774,585–122,775,777 | 70.6 kb | Distal (>10kb) Multiome | 798 | |
| chr5:122,844,391–122,846,095 | 27 bp | At TSS Multiome | 820 | |
| chr5:122,846,209–122,846,384 | 605 bp | At TSS | 249 | |
| chr5:122,846,985–122,847,120 | 1.4 kb | Proximal (<10kb) | 31 | |
| chr5:123,035,334–123,037,434 | 191.2 kb | Distal (>10kb) Multiome | 780 | |
| chr5:123,088,080–123,091,125 | 244.7 kb | Distal (>10kb) Multiome | 570 | |
| chr5:123,093,515–123,094,439 | 248.4 kb | Distal (>10kb) Multiome | 126 | |
| chr5:123,097,777–123,100,237 | 254.1 kb | Distal (>10kb) Multiome | 307 |
Genomic view of the SNX24 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.