Predicted to be involved in RNA processing. Predicted to be located in Cajal body and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNHG22. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNHG22 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNHG22, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr18:49,491,896–49,492,680 | 321.6 kb | Distal (>10kb) Multiome HiCAR | 825 | |
| chr18:49,527,826–49,528,357 | 285.9 kb | Distal (>10kb) Multiome HiCAR | 61 | |
| chr18:49,560,867–49,562,777 | 252.1 kb | Distal (>10kb) Multiome | 537 | |
| chr18:49,613,011–49,613,628 | 200.7 kb | Distal (>10kb) Multiome | 220 | |
| chr18:49,723,619–49,724,545 | 90.1 kb | Distal (>10kb) Multiome | 344 | |
| chr18:49,725,786–49,726,901 | 87.7 kb | Distal (>10kb) Multiome | 248 | |
| chr18:49,759,484–49,760,451 | 54.0 kb | Distal (>10kb) Multiome | 147 | |
| chr18:49,813,360–49,814,537 | 110 bp | At TSS Multiome | 858 | |
| chr18:49,905,054–49,905,920 | 91.4 kb | Distal (>10kb) Multiome | 75 | |
| chr18:49,911,085–49,912,315 | 97.6 kb | Distal (>10kb) Multiome | 185 | |
| chr18:49,959,032–49,959,704 | 145.4 kb | Distal (>10kb) Multiome | 100 |
Genomic view of the SNHG22 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.