Enables NAD transmembrane transporter activity. Involved in mitochondrial NAD transmembrane transport. Located in mitochondrion. Is active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC25A51. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC25A51 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC25A51, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:37,650,357–37,651,703 | 253.4 kb | Distal (>10kb) Multiome | 403 | |
| chr9:37,751,142–37,751,941 | 152.8 kb | Distal (>10kb) Multiome | 38 | |
| chr9:37,753,624–37,754,122 | 150.5 kb | Distal (>10kb) Multiome | 540 | |
| chr9:37,784,663–37,785,433 | 119.3 kb | Distal (>10kb) Multiome | 859 | |
| chr9:37,800,307–37,801,695 | 103.6 kb | Distal (>10kb) Multiome | 1104 | |
| chr9:37,903,405–37,904,985 | 135 bp | At TSS Multiome | 1045 | |
| chr9:37,913,669–37,914,191 | 9.5 kb | Proximal (<10kb) Multiome | 509 | |
| chr9:37,922,396–37,923,788 | 19.0 kb | Distal (>10kb) Multiome | 162 | |
| chr9:38,017,105–38,017,773 | 113.0 kb | Distal (>10kb) Multiome | 267 | |
| chr9:38,066,700–38,070,292 | 165.3 kb | Distal (>10kb) Multiome | 922 | |
| chr9:38,107,683–38,108,797 | 203.9 kb | Distal (>10kb) Multiome | 259 | |
| chr9:38,154,485–38,155,231 | 250.5 kb | Distal (>10kb) Multiome | 80 | |
| chr9:38,380,130–38,381,754 | 476.6 kb | Distal (>10kb) Multiome HiCAR | 696 | |
| chr9:38,392,279–38,393,206 | 488.3 kb | Distal (>10kb) Multiome HiCAR | 749 |
Genomic view of the SLC25A51 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.