Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for NPIPB13. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = NPIPB13 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of NPIPB13, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr16:29,961,477–29,962,530 | 293.3 kb | Distal (>10kb) Multiome | 848 | |
| chr16:29,973,238–29,974,906 | 281.6 kb | Distal (>10kb) Multiome | 935 | |
| chr16:29,994,888–29,996,728 | 259.1 kb | Distal (>10kb) Multiome | 1080 | |
| chr16:30,021,215–30,021,860 | 233.7 kb | Distal (>10kb) Multiome | 764 | |
| chr16:30,052,803–30,053,364 | 202.2 kb | Distal (>10kb) Multiome | 989 | |
| chr16:30,063,722–30,066,296 | 191.2 kb | Distal (>10kb) Multiome | 1209 | |
| chr16:30,075,490–30,076,439 | 179.3 kb | Distal (>10kb) Multiome | 828 | |
| chr16:30,090,881–30,092,910 | 162.4 kb | Distal (>10kb) Multiome | 1101 | |
| chr16:30,095,557–30,096,839 | 158.9 kb | Distal (>10kb) Multiome | 824 | |
| chr16:30,122,728–30,123,578 | 132.0 kb | Distal (>10kb) Multiome | 718 | |
| chr16:30,182,759–30,183,865 | 71.8 kb | Distal (>10kb) Multiome | 547 | |
| chr16:30,334,526–30,335,777 | 80.1 kb | Distal (>10kb) Multiome | 486 | |
| chr16:30,354,854–30,355,978 | 100.1 kb | Distal (>10kb) Multiome | 1070 | |
| chr16:30,369,220–30,371,611 | 115.5 kb | Distal (>10kb) Multiome | 818 | |
| chr16:30,377,495–30,379,532 | 123.1 kb | Distal (>10kb) Multiome | 1025 | |
| chr16:30,394,422–30,396,098 | 139.9 kb | Distal (>10kb) Multiome | 941 | |
| chr16:30,400,026–30,401,048 | 145.3 kb | Distal (>10kb) Multiome | 839 | |
| chr16:30,406,974–30,408,429 | 152.2 kb | Distal (>10kb) Multiome | 908 | |
| chr16:30,417,414–30,418,576 | 162.8 kb | Distal (>10kb) Multiome | 543 | |
| chr16:30,429,571–30,430,773 | 174.9 kb | Distal (>10kb) Multiome | 1060 | |
| chr16:30,445,340–30,446,062 | 190.6 kb | Distal (>10kb) Multiome | 898 | |
| chr16:30,526,068–30,527,896 | 272.1 kb | Distal (>10kb) Multiome | 1004 | |
| chr16:30,534,370–30,535,460 | 279.6 kb | Distal (>10kb) Multiome | 957 |
Genomic view of the NPIPB13 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.