MT-ND2

NADH dehydrogenase subunit 2 | NAD2, ND2, MTND2

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrial inner membrane. Part of respiratory chain complex I. Implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-9 DE-9.4 Developmental clusters: GC3

Biological processes 25 terms

NADH dehydrogenase (ubiquinone) activity (GO:0008137)NADH dehydrogenase (ubiquinone) activity (GO:0008137)NADH dehydrogenase (ubiquinone) activity (GO:0008137)NADH dehydrogenase (ubiquinone) activity (GO:0008137)aerobic respiration (GO:0009060)ionotropic glutamate receptor binding (GO:0035255)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial respiratory chain complex I assembly (GO:0032981)mitochondrion (GO:0005739)protein binding (GO:0005515)protein kinase binding (GO:0019901)proton motive force-driven mitochondrial ATP synthesis (GO:0042776)proton transmembrane transport (GO:1902600)respiratory chain complex I (GO:0045271)respiratory chain complex I (GO:0045271)respiratory chain complex I (GO:0045271)respiratory chain complex I (GO:0045271)response to hypoxia (GO:0001666)

Expression (TPM)