MT-ATP6

ATP synthase F0 subunit 6 | ATP6, ATPase-6, Su6m, MTATP6, RP

Enables proton channel activity. Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in proton motive force-driven mitochondrial ATP synthesis and proton transmembrane transport. Located in mitochondrion. Part of proton-transporting ATP synthase complex. Implicated in Leber hereditary optic neuropathy; NARP syndrome; Parkinson's disease; multiple sclerosis; and systemic lupus erythematosus. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-9 DE-9.4 Developmental clusters: GC3

Biological processes 20 terms

mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrion (GO:0005739)mitochondrion (GO:0005739)protein binding (GO:0005515)proton channel activity (GO:0015252)proton motive force-driven ATP synthesis (GO:0015986)proton motive force-driven ATP synthesis (GO:0015986)proton motive force-driven ATP synthesis (GO:0015986)proton motive force-driven ATP synthesis (GO:0015986)proton motive force-driven mitochondrial ATP synthesis (GO:0042776)proton transmembrane transport (GO:1902600)proton transmembrane transporter activity (GO:0015078)proton-transporting ATP synthase activity, rotational mechanism (GO:0046933)proton-transporting ATP synthase activity, rotational mechanism (GO:0046933)proton-transporting ATP synthase complex (GO:0045259)proton-transporting ATP synthase complex (GO:0045259)proton-transporting ATP synthase complex (GO:0045259)response to hyperoxia (GO:0055093)

Expression (TPM)