TFs regulating MIR29B2CHG 0 TFs

Transcription factors with Perturb-seq knockdown data for MIR29B2CHG. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MIR29B2CHG upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to MIR29B2CHG

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MIR29B2CHG, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr1:207,579,217–207,579,858	289.6 kb	Distal (>10kb) Multiome	258
chr1:207,633,750–207,634,299	235.2 kb	Distal (>10kb) Multiome	77
chr1:207,644,651–207,646,070	224.1 kb	Distal (>10kb) Multiome	404
chr1:207,751,438–207,753,038	117.2 kb	Distal (>10kb) Multiome	886
chr1:207,868,258–207,869,634	33 bp	At TSS Multiome	605
chr1:207,958,821–207,959,846	90.3 kb	Distal (>10kb) Multiome	203
chr1:207,962,859–207,964,269	94.5 kb	Distal (>10kb) Multiome HiCAR	820
chr1:208,040,793–208,041,533	172.0 kb	Distal (>10kb) Multiome	20
chr1:208,054,734–208,055,741	186.0 kb	Distal (>10kb) Multiome	155
chr1:208,083,034–208,084,299	214.5 kb	Distal (>10kb) Multiome	259
chr1:208,119,310–208,121,028	251.0 kb	Distal (>10kb) Multiome	458
chr1:208,127,858–208,128,857	259.3 kb	Distal (>10kb) Multiome	35
chr1:208,131,666–208,132,496	263.1 kb	Distal (>10kb) Multiome	371

Genome Browser

Genomic view of the MIR29B2CHG locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.