Predicted to enable enzyme activator activity and ligase regulator activity. Predicted to be involved in several processes, including negative regulation of microtubule depolymerization; positive regulation of fatty acid biosynthetic process; and positive regulation of ligase activity. Predicted to be located in microtubule cytoskeleton. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for MID1IP1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MID1IP1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MID1IP1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chrX:38,560,880–38,562,705 | 240.0 kb | Distal (>10kb) Multiome | 366 | |
| chrX:38,801,060–38,801,744 | 116 bp | At TSS Multiome | 564 | |
| chrX:38,803,363–38,804,956 | 2.6 kb | Proximal (<10kb) Multiome | 888 | |
| chrX:39,017,708–39,018,344 | 216.5 kb | Distal (>10kb) Multiome HiCAR | 73 | |
| chrX:39,065,028–39,066,220 | 264.2 kb | Distal (>10kb) Multiome HiCAR | 245 | |
| chrX:39,150,486–39,151,208 | 349.3 kb | Distal (>10kb) Multiome HiCAR | 59 | |
| chrX:39,152,167–39,152,652 | 351.0 kb | Distal (>10kb) Multiome HiCAR | 253 |
Genomic view of the MID1IP1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.